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To date, there have been more than 160 case reports of CCDS1 [36]
The transcriptional program induced by cystine deprivation is similar to that of leucine starvation 14 , suggesting that the transcriptional program is a common adaptation of amino acid starvation to activate amino acid metabolism and stress resistance
However, these approaches produce much smaller metabolic effects compared to prescription semaglutide and should not be considered direct substitutes when medication is clinically indicated
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